Helicobacter Pylori And Non-alcoholic Fatty Liver Disease Is There A Relationship?

Document Type : Original Clinical

Authors

1 Department of Tropical Medicine and Infectious Diseases, Faculty of Medicine, Tanta University.

2 Department of Tropical Medicine and Infectious Diseases, Faculty of Medicine, Tanta University

3 Emergency Medicine and Intensive Care Specialist Nuremberg Hospital, Paracelsus Medical Private University

4 Department of public health, Faculty of medicine, Tanta University, Egypt

Abstract

Background and Aim: researchers proposed a connection between H pylori and obesity, diabetes, and improper lipid metabolism. The studies have discovered that H pylori infection is one of the elements for Non-Alcoholic Fatty liver Disease (NAFLD) to progress and that getting rid of Helicobacter pylori (H pylori) can partially stop the evolution of NAFLD. Other research, however, argues that there is no definitive link between H pylori infection and NAFLD. We aimed to investigate the prevalence of H pylori infection in NAFLD.
Materials and Methods: This study was conducted on 110 patients diagnosed with NAFLD by ultrasound and fibroscan. They were assessed for the diagnosis of H. pylori infection by H. pylori antigen in stool.
Results: The patients were classified into H pylori +ve group and H pylori -ve group. There was a significant difference between both groups regarding sex (p = 0.01) and diabetes mellitus (p = 0.000) and no significant difference between both groups as regard smoking, hypertension, and BMI. There was significant difference between both groups regarding steatosis (p = 0.0001) and fibrosis grade (p = 0.0001)
Conclusion: the prevalence of H. Pylori has increased in NAFLD; also, H. pylori may be an independent risk factor for NAFLD.

Keywords

Main Subjects

Files

Share

How to cite

Statistics