CHRONIC HELICOBACTER PYLORI GASTRITIS: OLGA AND OLGIM SCORES IN THREE HOSPITAL CENTERS IN ABIDJAN (COTE D'IVOIRE)

Document Type : Original Clinical

Authors

1 Felix Houphouët-Boigny University Hospital.

2 Angre University Hospital.

Abstract

Background and aim: The Operative Link on Gastritis Assessment (OLGA) and Operative Link on Gastritis Intestinal Metaplasia Assessment (OLGIM) scores are used, in addition to the Sydney system, for chronic gastritis caused by Helicobacter pylori (H. pylori). They enable the grading of histological lesions of glandular atrophy and intestinal metaplasia, which are associated with low and high risk of neoplastic degeneration, respectively. We evaluated chronic Helicobacter pylori gastritis according to OLGA and OLGIM scores, and investigated the factors related to the occurrence of severe histological lesions.
Patients and methods: We conducted an analytical cross-sectional study from January 1, 2023, to June 30, 2023. Included were adult patients of both sexes who presented with chronic Helicobacter pylori gastritis, diagnosed by histological analysis of gastric biopsies. The re-evaluation of atrophy and intestinal metaplasia of the Sydney System parameters made it possible to define OLGA and OLGIM stages, respectively. The significance threshold retained was set at p < 0.05.
Results: Our study included 346 patients with a mean age of 44.4 ± 14.2 years and a sex ratio of 0.71. Lesions of glandular atrophy and intestinal metaplasia were present in the antrum in 32.4% and 12.7% of cases, respectively. Stage III disease represented 2.0% of the cases according to the OLGA score and 0.6% of the cases according to the OLGIM score. None of the patients had a stage IV disease. 
Conclusion: Severe histological lesions (OLGA-OLGIM III and IV) are rare, despite the high prevalence of Helicobacter pylori infection.

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Footnotes. Ahmed Fathy (Professor of internal medicine, gastroenterology, and hepatology unit), Hayam Rashed (Professor of pathology), and Amany Mohamed (Professor of family medicine and biostatistician) were peer reviewers. E- Editor: Salem Youssef Mohamed, Osama Ahmed Khalil, Amany Mohammed. Copyright ©. This open-access article is distributed under the Creative Commons Attribution License (CC BY). It may be used, distributed, or reproduced in other forums, provided the original author(s) and the copyright owner(s) are credited. The original publication in this journal must be cited according to accepted academic practice. Disclaimer: The authors' claims in this article are solely their own and do not necessarily represent their affiliated organizations or those of the publisher, the editors, or the reviewers. Any product evaluated in this article or its manufacturer's claim is not guaranteed or endorsed by the publisher. Ethics approval: Informed consents were obtained from all individuals involved in this work. Data and materials availability: The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request. Competing interests: The authors declare that they have no competing interests. Funding: This study had no funding from any source. This work was conducted following the STROBE guidelines. Authors' contributions: All authors made substantial contributions to the study's conception, design, data acquisition, analysis, or interpretation; drafting or revising the article; and final approval of the version to be submitted. Acknowledgments: none.

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