PATHOLOGY AND MEDICINAL PLANT TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE

Document Type : Reviews Articles

Authors

Biology Department, College of Science, Zakho University, Zakho, Duhok, Kurdistan Region, Iraq.

Abstract

Gastroesophageal reflux disease (GERD) is a prevalent chronic disorder characterized by the backflow of acidic gastric contents into the esophagus due to lower esophageal sphincter (LES) dysfunction. This condition causes esophageal mucosal damage, leading to symptoms such as heartburn and chest pain, and is associated with increased risks of severe complications, including esophageal adenocarcinoma.
Aims:
To review the current state of GERD management and assess the potential of photochemical plant-based treatments as alternatives to conventional therapies.
Methods:
A comprehensive literature review was performed to describe the status of GERD in detail while focusing on the emerging role of plant-based therapies in GERD management.
Results:
Traditional treatments for GERD are effective but often come with side effects and limitations. Plant-based treatments, particularly those with photochemical properties, are potential complementary therapies. Preliminary data suggest these alternatives may improve symptom management and patient outcomes.
Conclusions:
While standard treatments for GERD are widely used, their limitations necessitate exploring alternative options. Photochemical plant-based therapies offer a promising, supplementary approach, pending further validation through research and clinical trials.

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Footnotes. Ahmed Gad (lecturer of internal medicine) and Ayman Sadek (assistant professor of internal medicine) were the peer reviewers. E- Editor: Salem Youssef Mohamed, Osama Ahmed Khalil, Amany Mohammed. Copyright ©. This open-access article is distributed under the Creative Commons Attribution License (CC BY). It may be used, distributed, or reproduced in other forums, provided the original author(s) and the copyright owner(s) are credited. The original publication in this journal must be cited according to accepted academic practice. Disclaimer: The authors' claims in this article are solely their own and do not necessarily represent their affiliated organizations or those of the publisher, the editors, and the reviewers. Any product evaluated in this article or its manufacturer's claim is not guaranteed or endorsed by the publisher. Ethical approval: All procedures involving human participants followed the institutional and national research committee's moral standards, the 1964 Helsinki Declaration, and its later amendments or comparable ethical standards. All authors declare that consent was obtained from the patient (or other approved parties) to publish this study. Data and materials availability: The datasets used or analyzed during the current study are available from the corresponding author upon reasonable request. Competing interests: The authors declare that they have no competing interests. Funding: This study had no funding from any resource. This work was done according to the STROBE guidelines. Authors’ contributions All authors thoroughly reviewed and approved the final version of the manuscript. Acknowledgment: I sincerely thank Assistant Professor Dr. Khalid Ibrahim for his valuable comments on this manuscript.

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